Course
This seminar is jointly organized by ThermoFisher Scientific (HK) and the Department of Diagnostic Sciences at HKMU.
Deadline of Registration: 29 May 2026 23:59
Speaker 1 | Speaker 2 | |||
|---|---|---|---|---|
Name | Dr LAM, Amy | | Dr CHAN, Lo Kong | | ||
Position | Field Application Scientist | | Scientific Officer (Medical) | | ||
Affiliation | ThermoFisher Scientific (HK) | | Division of Anatomical Pathology, Department of Pathology, QMH | | ||
Seminar Title | Companion Diagnostics: Co-development of Targeted Therapies with NGS and Digital PCR based Tests | | Implementing NGS in Routine Lung Cancer Testing: A Companion Diagnostic Approach for Identifying Actionable Mutations | | ||
Abstract | Companion diagnostics (CDx) have become essential in precision oncology, enabling the identification of patients most likely to benefit from targeted therapies while minimizing unnecessary treatment. This seminar explores the integrated co-development of therapeutic agents and molecular diagnostics, emphasizing the role of next-generation sequencing (NGS) and digital PCR (dPCR) in enhancing predictive accuracy and clinical decision-making. Key topics include regulatory and clinical development frameworks, analytical validation of biomarker assays, and the translation of genomic insights into actionable treatment strategies. The discussion highlights how NGS offers broad genomic profiling for patient stratification, while dPCR provides ultra-sensitive, quantitative detection for residual disease monitoring and resistance mutation tracking. The seminar aims to provide an updated perspective on the evolving landscape of CDx development, the challenges of aligning assay design with drug development timelines, and the opportunities for implementing these technologies in routine clinical practice to advance personalized cancer care. | Next-generation sequencing (NGS) has become integral to molecular diagnostics in different human cancers, which enables comprehensive detection of actionable mutations that guide targeted therapy. This presentation focuses on the implementation of NGS as a companion diagnostic approach in routine testing of non-small cell lung cancer (NSCLC). Clinically relevant alterations in NSCLC driver genes such as EGFR, ALK, ROS1, and others, will be highlighted in the context of targeted therapies. Key components of the NGS workflow including pre-analytical sample assessment, assay design, sequencing, and result interpretation will be outlined. Practical challenges in routine laboratory settings, including sample quality, turnaround time, and quality assurance, will also be addressed. Through selected examples, how NGS-based companion diagnostics enable efficient identification of actionable mutations and support timely, personalized treatment strategies in lung cancer care will be demonstrated. |
Online Webinar Course
ZOOM線上參加者，請遵循以下指示：
您必須
1) 使用我們在本訊息中提供給您的 ZOOM 邀請連結"Join Webinar" 及 在 ConEdu 中使用的註冊電郵加入 ZOOM Webinar。
[這將確保您的身份（即您的電子郵件地址）與在 ConEdu 平台上使用的身份相符。如果您使用的是其他不被識別的電子郵件地址，您的出席將無法得到驗證]。
2) 確保您的網路連線穩定且建立正常。延遲進入網路研討會或長時間斷線，可能不符合完成網路研討會以獲得 HK MLT CPD 學分(審批中)的要求 。
3) 在 ZOOM 環節中回答投票問題，並於會後在 ConEdu 平台上完成一組問卷調查(Survey*)，以確認其參與活動的有效性。若未能完成任何一項任務，將無法獲得 CPD 點數及/或出席證書。
*Survey: 問卷將顯示於您的 ConEdu 帳戶中。請點擊左側面板的「Enrolls」→ 在表格中找到並點擊「Survey」。
注意：為了支持環境的可持續性，電子出席證書將於短期內發佈到您在 ConEdu 系統中的帳戶，您可從該帳戶檢索證書。
ZOOM on-line participant, please follow the instruction below:
You shall
1) Use the ZOOM Invitation link that we provide you in this message AND the registered email address (the same email address used in ConEdu) to join the ZOOM Webinar.
(This shall ensure that your identity (ie. your email address) matches with that used in the ConEdu platform. If you use the other unrecognized email address, your attendance would not be verified.)
2) Make sure your network connection is stable and properly established. A delay in admission to the Webinar or a prolonged disconnection may not meet the requirements for completing the Webinar to receive HK MLT CPD points (approval pending).
3) Answer the polling question(s) during the ZOOM session and complete a set of Survey* questions (at the ConEdu platform) afterward to validate their participation in the event. Failure to complete either task will result in not being awarded the CPD points and/or the Certificate of Attendance.
*Survey questions will be available at your ConEdu account. Click "Enrolls" on the left panel --> find and click "Survey" at the table.
Note: To support environmental sustainability, the Certificate of Attendance (electronic copy only) will be released shortly to your account in the ConEdu system, from which you can retrieve the certificate.
Onsite In-person Course
成功完成註冊的現場參與者將透過電郵收到進入香港都會大學主校區的入場 QR 碼。
CPD活動結束後，現場參與者須於 ConEdu 平台上完成一組問卷調查(Survey*)。若未能完成任何一項任務，將無法獲得 CPD 點數及/或出席證書。
*Survey: 問卷將顯示於您的 ConEdu 帳戶中。請點擊左側面板的「Enrolls」→ 在表格中找到並點擊「Survey」。
注意：為了支持環境的可持續性，電子出席證書將於短期內發佈到您在 ConEdu 系統中的帳戶，您可從該帳戶檢索證書。
In-person participants who successfully register will be provided with an Access QR code for entry to the HKMU Campus.
After the CPD event, in-person participant(s) shall complete a set of Survey* questions (at the ConEdu platform). Failure to complete either task will result in not being awarded the CPD points and/or the Certificate of Attendance.
*Survey questions will be available at your ConEdu account. Click "Enrolls" on the left panel --> find and click "Survey" at the table.
Note: To support environmental sustainability, the Certificate of Attendance (electronic copy only) will be released shortly to your account in the ConEdu system, from which you can retrieve the certificate.
Ho Man Tin, Kowloon, Hong Kong
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